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Ahmad48Talented

Asked: April 16, 2024In: Health and Wellness

How do statins inhibit the HMG-CoA reductase enzyme, leading to reduced cholesterol production?

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How do statins inhibit the HMG-CoA reductase enzyme, leading to reduced cholesterol production?

Explain how statins inhibit the HMG-CoA reductase enzyme to reduce cholesterol synthesis. Discuss how statins block the conversion of HMG-CoA to mevalonate, a crucial step in cholesterol biosynthesis, ultimately leading to decreased intracellular cholesterol levels, upregulation of LDL receptors, and ...