I’m fascinated by the intricate specificity of antimalarial drugs, which selectively target the malaria parasite while sparing healthy cells in the human body. Could you please shed some light on the precise molecular mechanisms or cellular pathways that enable this ...
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Explain how statins inhibit the HMG-CoA reductase enzyme to reduce cholesterol synthesis. Discuss how statins block the conversion of HMG-CoA to mevalonate, a crucial step in cholesterol biosynthesis, ultimately leading to decreased intracellular cholesterol levels, upregulation of LDL receptors, and ...