Provide insights into how antipsychotic drugs alleviate symptoms of schizophrenia and other mental disorders. Discuss how antipsychotics block dopamine receptors, particularly D2 receptors, in the central nervous system, thereby alleviating positive symptoms of psychosis.
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How do azole antifungal drugs disrupt fungal cell growth and viability? Discuss how these medications inhibit lanosterol 14-alpha-demethylase, a crucial enzyme in ergosterol biosynthesis, leading to compromised fungal cell membrane integrity and eventual cell death, making them effective in treating ...